Mini Review Study of Antitubercular Drugs of Nicotinamide, Thioisonicotinamide and Pyrazinamide Derivatives
نویسنده
چکیده
The tuberculosis is a typically chronic infection caused by Mycobacterium tuberculosis. The progress of effective treatment of tuberculosis (TB) has been recently due to alarm regarding the appearance of vastly drug-resistant TB strains. The efforts that gave rise to current first line and second-line anti-TB drugs in global use today and attempts to summarize ongoing discovery being conducted. The TB has different disease-specific concerns and control that introduce major complexity in drug discovery efforts. In this article a brief discussion about nicotinamide, thioisonicotinamide and pyrazinamide analogues for the better and effect TB treatment particular against resistance mycobacterium strains.
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